
Thermo Fisher Scientific MIRK Polyclonal Antibody
Thermo Fisher Scientific의 MIRK Polyclonal Antibody는 인간 DYRK1B 단백질을 표적하는 고품질 Rabbit IgG 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 5–15 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 500 and 550 of human minibrain-related kinase (DYRK1B, UniProt ID: Q9Y463-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
DYRK1B is a member of the DYRK family of protein kinases and is proposed to be involved in nuclear functions. Integrins are heterodimers comprised of alpha and beta subunits that are noncovalently associated transmembrane glycoprotein receptors. Integrins mediate cell-matrix or cell-cell adhesion and transduce signals that regulate gene expression and cell growth. DYRK1B encodes the integrin beta 4 subunit, a receptor for laminins. Mutations in DYRK1B are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for DYRK1B.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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