Thermo Fisher Scientific CD71 (Transferrin Receptor) VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1205)
CD71(Transferrin Receptor)에 특이적인 알파카 유래 재조합 단일클론 항체로 인간 시료에 반응. WB, Flow Cytometry, ELISA에 사용 가능. CHO 세포에서 발현되며 Metal-chelate chromatography로 정제. 연구용으로만 사용.
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- MA554512
- 판매단위
- pk
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Thermo Fisher Scientific CD71 (Transferrin Receptor) VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1205)
Applications
- Western Blot (WB): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- ELISA: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1205 |
| Immunogen | Recombinant Human CD71/TFRC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor.
Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome, and in HIV patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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