Thermo Fisher Scientific PRMT2 Polyclonal Antibody
Thermo Fisher Scientific의 PRMT2 Polyclonal Antibody는 인간 PRMT2 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot 및 ChIP assay에 적합합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific PRMT2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| ChIP assay (ChIP) | 0.5 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human PRMT2 (aa 71–120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608487 |
Product Specific Information
- Peptide sequence: ERAGCCGYIP ANHVGKHVDE YDPEDTWQDE EYFGSYGTLK LHLEMLADQP
- Sequence homology: Human: 100%; Rat: 79%
Target Information
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4.
Acts as a coactivator (with NCOA2) of androgen receptor (AR)-mediated transactivation and as a coactivator of estrogen receptor (ER)-mediated transactivation.
Enhances PGR, PPARG, RARA-mediated transactivation.
May inhibit NF-kappa-B transcription and promote apoptosis.
Represses E2F1 transcriptional activity (in a RB1-dependent manner).
May be involved in growth regulation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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