Thermo Fisher Scientific CALB1 Polyclonal Antibody, MaxPab

Applications

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MAESHLQSSL ITASQFFEIW LHFDADGSGY LEGKELQNLI QELQQARKKA GLELSPEMKT FVDQYGQRDD GKIGIVELAH VLPTEENFLL LFRCQQLKSC EEFMKTWRKY DTDHSGFIET EELKNFLKDL LEKANKTVDD TKLAEYTDLM LKLFDSNNDG KLELTEMARL LPVQENFLLK FQGIKMCGKE FNKAFELYDQ DGNGYIDENE LDALLKDLCE KNKQDLDINN ITTYKKNIMA LSDGGKLYRT DLALILCAGD N

Target Information

Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin) is a highly conserved 28 kDa calcium-binding protein with broad tissue distribution. It belongs to a family of low molecular weight calcium-binding proteins (CaBPs), including calmodulin, S-100, parvalbumin, and troponin C. These CaBPs share homologous EF-hand motifs for Ca²⁺ binding.
Calbindin-D-28K is predominantly found in subpopulations of central and peripheral nervous system neurons, and in epithelial cells involved in Ca²⁺ transport such as distal tubular cells and cortical collecting tubules of the kidney, as well as in enteric neuroendocrine cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.