Thermo Fisher Scientific CELSR3/Flamingo Homolog 1 Polyclonal Antibody

Applications

Western Blot (WB)

• Assay-dependent

Immunoprecipitation (IP)

• 2–10 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

Target Information

CELSR3 is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins that do not interact with catenins. These cadherins are located at the plasma membrane and possess nine cadherin domains, seven EGF-like repeats, and two laminin A G-type repeats in their ectodomain. They also feature seven transmembrane domains, unique to this subfamily. It is suggested that these proteins act as receptors in contact-mediated communication, with cadherin domains functioning in homophilic binding and EGF-like domains involved in adhesion and ligand interactions. The specific function of CELSR3 remains undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.