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Thermo Fisher Scientific BACE2 Polyclonal Antibody
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Thermo Fisher Scientific BACE2 Polyclonal Antibody

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Rabbit polyclonal antibody targeting human BACE2 protein for WB and IHC applications. Recognizes APP cleavage sites involved in Alzheimer’s disease research. Supplied as unconjugated liquid, 0.5 mg/mL, stored at 4°C or -20°C. For research use only.

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pk
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마지막 업데이트 2025. 08. 02. 오전 01:53
Thermo Fisher Scientific PA130765 BACE2 Polyclonal Antibody 100 ug pk판매 단위 pk ·
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787,800원VAT 포함 866,580원

Thermo Fisher Scientific · Thermo Fisher Scientific BACE2 Polyclonal Antibody

Thermo Fisher Scientific BACE2 Polyclonal Antibody

Applications

  • Western Blot (WB): 1:500–1:1,000
  • Immunohistochemistry (IHC): Assay-dependent

Product Specifications

항목 내용
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide APTPGPGTPAERHADG, corresponding to amino acids 44–59 of Human BACE2
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Wet ice
RRID AB_1956252

Product Specific Information

  • Recommended positive control: Human heart tissue lysate
  • Store product as a concentrated solution.
  • Centrifuge briefly prior to opening the vial.

Target Information

BACE2 (Beta Secretase 2) is responsible for the proteolytic processing of amyloid precursor protein (APP).
It cleaves APP between residues 690–691, generating and releasing beta-cleaved soluble APP.
BACE2 also cleaves APP between residues 671–672.
Accumulation of APP is a hallmark of Alzheimer’s disease and a frequent complication in adult Down syndrome patients.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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