Thermo Fisher Scientific CCR1 Polyclonal Antibody
Thermo Fisher Scientific의 CCR1 Polyclonal Antibody는 마우스 및 랫트 단백질에 반응하며, Western blot, IHC, ELISA, IP에 적합합니다. 합성 펩타이드 면역원으로 제작된 비결합 액상 항체로, 높은 특이성과 안정성을 제공합니다.
- 카탈로그번호
- CCR1-101AP
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1–50 of mouse CCR1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Chemokines are key mediators of inflammation and play crucial roles in recruiting effector immune cells to infection sites. They activate leukocytes through G protein–coupled receptors, classified mainly as CXCR and CCR families.
CCR1, a member of the CCR receptor group, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils. It binds macrophage-inflammatory protein (MIP-1), eotaxin, and other related chemokines.
Mice lacking CCR1 show impaired neutrophil trafficking and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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