Thermo Fisher Scientific BNIP3 Polyclonal Antibody
BNIP3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 등에 사용 가능. Human, Mouse, Rat 반응성. 동결건조 형태로 제공되며 재구성 시 500 µg/mL 농도. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공.
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Applications
- Western Blot (WB): 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human BNIP3 (38–53aa, IYNGDMEKILLDAQHE) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745998 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
NIP3 (BNIP3) is a member of the BCL2/adenovirus E1B 19 kDa-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects against virally induced cell death, as well as BCL2, another apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain associated with pro-apoptotic function. This dimeric mitochondrial protein induces apoptosis even in the presence of BCL2.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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