Thermo Fisher Scientific SH3BP1 Polyclonal Antibody
인간 SH3BP1 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 0.1 mg/mL 농도의 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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- PA581891
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SH3BP1. Recombinant protein control fragment (Product # RP-91341) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789052 |
Product Specific Information
Immunogen sequence:
ENLSNLRYLM KFLARLAEEQ EVNKMTPSNI AIVLGPNLLW PPEKEGDQAQ LDAASVSSIQ VVGVVEALIQ SADTLFPGDI NFNVSGLFSA VTLQDTVSDR LASEELPSTA VPTPATTPAP APAPAPAPAP ALASAATKER TESEVPP
Target Information
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC, and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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