Thermo Fisher Scientific Apolipoprotein C-I Polyclonal Antibody

Applications

ELISA (ELISA)

• Tested Dilution: 1:5,000 - 1:10,000

Product Specifications

Product Specific Information

• This product is stable at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.
• For extended storage, mix with an equal volume of glycerol, aliquot contents, and freeze at -20°C or below.

Target Information

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins.
The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver, where it is activated when monocytes differentiate into macrophages.
The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single-chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues.
The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase.
The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.