Thermo Fisher Scientific Inhibin alpha Polyclonal Antibody, Biotin
Biotin으로 표지된 Inhibin alpha 폴리클론 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 고순도의 Affinity chromatography 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Inhibin alpha Polyclonal Antibody, Biotin
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides corresponding to amino acid regions 1–50 and 220–270 on Inhibin alpha gene |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA and 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibin alpha subunit combines with either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity. Serum inhibin levels correlate with granulosa-cell tumor size, serving as a marker for primary and recurrent disease. In prostate cancer, inhibin alpha-subunit gene expression is suppressed and undetectable in poorly differentiated cells. Expression varies across tissues, suggesting inhibin functions as both a growth/differentiation factor and a hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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