Thermo Fisher Scientific CD336 (NKp44) Monoclonal Antibody (44.189), APC, eBioscience
인간 CD336(NKp44, NCR2)을 인식하는 마우스 단클론 항체로, APC 형광 접합체 형태입니다. IL-2 자극 NK 세포 및 다양한 면역세포에서의 발현 분석에 적합하며, 유세포분석(Flow Cytometry)에 최적화되어 있습니다. 4°C 암조건 보관, 동결 금지.
- 카탈로그번호
- 17-3369-42
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD336 (NKp44) Monoclonal Antibody (44.189), APC, eBioscience
Thermo Fisher Scientific CD336 (NKp44) Monoclonal Antibody (44.189), APC, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.25 µg)/test
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Recommended Isotype Control | Mouse IgG2b kappa Isotype Control (eBMG2b), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 44.189 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2573202 |
Additional Formats
- eFluor 450
- Functional Grade
- PE
- PerCP-eFluor 710
- Request custom conjugation
Product Specific Information
The monoclonal antibody 44.189 reacts with human CD336 (NKp44, NCR2), a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family. It contains an ITIM domain in the cytoplasmic tail and requires association with DAP12, an ITAM-containing accessory protein, for NK cell activation.
CD336 expression has been observed on:
- IL-2-activated NK cells
- IL-3-stimulated plasmacytoid dendritic cells
- αβ T cells in small intestinal epithelium
- T cells in cord blood
This antibody facilitates CD336 crosslinking and is validated for flow cytometric analysis.
Pre-titrated for use at 5 µL (0.25 µg)/test on IL-2-stimulated human peripheral blood cells.
Excitation: 633–647 nm; Emission: 660 nm; Laser: Red Laser.
Filtered post-manufacturing (0.2 µm).
Target Information
CD336 (NKp44, NCR2) plays a key role in innate immune responses of activated NK cells against viral infections and tumor proliferation.
Expression and activation require DAP12 association.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.