Thermo Fisher Scientific Cytokeratin 5/6 (Basal, Myoepithelial and Mesothelial Cell Marker) Monoclonal Antibody (KRT5.6/4866)
사이토케라틴 5/6 단클론 항체(KRT5.6/4866)는 인간 기저, 근상피 및 중피세포 마커 검출용으로 개발되었습니다. IHC(P) 및 IHC(PFA) 실험에 적합하며, 단백질 A/G로 정제된 1 mg/mL 농도의 비결합 항체입니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT5.6/4866 |
| Immunogen | Recombinant full-length human KRT5 protein (Cytokeratin 5/6, UniProt ID: P13647-1, Antigen range: 1–590) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
Target Information
The protein encoded by this gene is a member of the keratin gene family.
Type II cytokeratins consist of basic or neutral proteins arranged in pairs of heterotypic keratin chains coexpressed during differentiation of epithelial tissues.
This cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14.
Mutations in these genes are associated with epidermolysis bullosa simplex.
Type II cytokeratins are clustered in a region of chromosome 12q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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