Thermo Fisher Scientific PSD4 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human PSD4 protein. Validated for IHC (paraffin) with dilution 1:50–1:200. Antigen affinity purified, supplied in PBS with glycerol and sodium azide. Suitable for research use in membrane trafficking and ARF6 path...
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PSD4. Recombinant protein control fragment (Product # RP-96071) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646045 |
Product Specific Information
Immunogen sequence:
EESMFFSNPL FLASPCSENS ASGECFSWGA SDSHAGVRTG PESPATLEPP LPEDTVLWEL ESEPDLGDGA AISGHCTPPF PVPIYKPHSI
Highest antigen sequence identity to the following orthologs:
- Mouse: 56%
- Rat: 55%
Target Information
PSD4 acts as a guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, it controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells and is involved in membrane recycling. It interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate, and phosphatidylinositol 4,5-bisphosphate. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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