Thermo Fisher Scientific Phospho-EGFR (Tyr1068) Recombinant Rabbit Monoclonal Antibody (EGFRY1068-E5), FITC

Applications

• Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
• View 1 publication

Product Specifications

Additional Formats

• Unconjugated
• APC
• PE
• Request custom conjugation

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone the specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal clones for production.
Advantages include:

• Enhanced specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the rabbit immune repertoire

Target Information

EGFR (epidermal growth factor receptor) is a receptor tyrosine kinase that mediates signaling in response to various growth factors. Overexpression is associated with multiple cancers and serves as a target for biological and small-molecule therapeutics.
EGFR is encoded by the EGFR gene on chromosome 7 and belongs to the HER/ERbB family (ERbB2, ERbB3, ERbB4). Ligand binding (e.g., EGF, TGFα) induces receptor dimerization and autophosphorylation of tyrosine residues.
Overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, and squamous cell carcinoma.

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.

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