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ELK Biotechnology IRF-3 rabbit pAb
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IRF-3 rabbit pAb는 인간 IRF3 단백질을 인식하는 고품질 폴리클로날 항체입니다. WB, IHC, IF, ELISA에 사용 가능하며, 세포 내 IRF3의 발현 및 위치 연구에 적합합니다. 인간, 마우스, 랫트, 돼지 시료에 반응합니다.
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ELK Biotechnology ES5924-100UL IRF-3 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES5924-50UL IRF-3 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology IRF-3 rabbit pAb
제품명
IRF-3 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | IRF3; Interferon regulatory factor 3; IRF-3 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 Immunofluorescence: 1/200–1/1000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IRF3 (AA range: 351–400) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 48–55 kDa |
| Gene ID (Human) | 3661 |
| Human Swiss-Prot No. | Q14653 |
| Cellular Localization | Cytoplasm, Nucleus, Mitochondrion. Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect (PubMed:10805757). When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm (PubMed:10805757). Recruited to mitochondria via TOMM70:HSP90AA1 upon Sendai virus infection (PubMed:25609812). |
| Species Reactivity | Human; Rat; Mouse; Pig |
Background
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that, upon serine/threonine phosphorylation, forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (Provided by RefSeq, Nov 2011)
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