ELK Biotechnology Hck (phospho Tyr410) rabbit pAb
Hck (phospho Tyr410) rabbit pAb는 인간 HCK의 Tyr410 인산화 부위를 인식하는 폴리클로날 항체입니다. IHC, IF, ELISA에 적합하며 높은 특이성과 재현성을 제공합니다. 인간, 마우스, 랫트에 반응하며 -20°C에서 1년간 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology Hck (phospho Tyr410) rabbit pAb
제품명
Hck (phospho Tyr410) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | HCK; Tyrosine-protein kinase HCK; Hematopoietic cell kinase; Hemopoietic cell kinase; p59-HCK/p60-HCK; p59Hck; p61Hck |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HCK around the phosphorylation site of Tyr410 (AA range: 381–430) |
| Species | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 3055 |
| Human Swiss-Prot No | P08631 |
| Species Reactivity | Human; Mouse; Rat |
세포 내 위치 (Cellular Localization)
Isoform 1: Lysosome, membrane (lipid-anchor), cell projection (podosome membrane), cytoplasm (cytosol). Associated with specialized secretory lysosomes called azurophil granules. At least half of this isoform is found in the cytoplasm, some fraction is myristoylated.
Isoform 2: Cell membrane (lipid-anchor), membrane (caveola), cell junction (focal adhesion), cytoplasm (cytoskeleton), Golgi apparatus, cytoplasmic vesicle, lysosome, nucleus. 20% of this isoform is associated with caveolae. Localization at the cell membrane and caveolae requires palmitoylation at Cys-3. Colocalizes with the actin cytoskeleton at focal adhesions. Also found in cytoplasmic vesicle (secretory vesicle) and cytosol.
Background
The protein encoded by this gene is a member of the Src family of tyrosine kinases. It is primarily hemopoietic, expressed in myeloid and B-lymphoid lineages. It may help couple the Fc receptor to activation of the respiratory burst and play roles in neutrophil migration and degranulation. Multiple isoforms with distinct subcellular distributions are produced through alternative splicing and use of alternative translation initiation codons, including a non-AUG (CUG) codon.
[provided by RefSeq, Feb 2010]
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.