ELK Biotechnology IRF-3 (phospho Ser396) rabbit pAb
IRF-3 (phospho Ser396) rabbit polyclonal antibody로, 인산화된 IRF-3 단백질 검출에 적합합니다. WB와 IHC에 사용 가능하며, Human, Mouse, Rat에 반응합니다. 세포 내 위치 연구 및 인터페론 관련 신호전달 연구에 활용됩니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology IRF-3 (phospho Ser396) rabbit pAb
ELK Biotechnology IRF-3 (phospho Ser396) rabbit pAb
제품 설명
IRF-3 (phospho Ser396) rabbit polyclonal antibody는 인산화된 IRF-3 단백질을 특이적으로 인식하는 항체로, 인터페론 조절 인자 연구 및 신호전달 경로 분석에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | IRF-3 (phospho Ser396) rabbit pAb |
| Alternative Names | IRF3; Interferon regulatory factor 3; IRF-3 |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | Synthesized peptide derived from human IRF-3 around the phosphorylation site of Ser396 (AA range: 362–411) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 48–55 kDa |
| GeneID (Human) | 3661 |
| Human Swiss-Prot No. | Q14653 |
| Cellular Localization | Cytoplasm, Nucleus, Mitochondrion. Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect (PubMed:10805757). When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm (PubMed:10805757). Recruited to mitochondria via TOMM70:HSP90AA1 upon Sendai virus infection (PubMed:25609812). |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.