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ELK Biotechnology IL-2Rβ (phospho Tyr364) rabbit pAb
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IL-2Rβ (phospho Tyr364) rabbit polyclonal antibody로, IL-2 수용체 베타 소단위의 인산화 부위를 인식합니다. WB, IF, ELISA에 사용 가능하며, 인간, 마우스, 랫트에 반응합니다. 세포막 단일 통과형 단백질 검출에 적합합니다.
- 판매단위
- pk
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ELK Biotechnology ES5872-100UL IL-2Rβ (phospho Tyr364) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES5872-50UL IL-2Rβ (phospho Tyr364) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology IL-2Rβ (phospho Tyr364) rabbit pAb
제품명
IL-2Rβ (phospho Tyr364) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | IL2RB; Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; High affinity IL-2 receptor subunit beta; p70-75; p75; CD antigen CD122 |
| Applications | WB; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human IL-2R beta around the phosphorylation site of Tyr364 (AA range: 331-380) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 61 kD |
| Gene ID (Human) | 3560 |
| Human Swiss-Prot No. | P14784 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, exists in three forms based on its binding affinity for interleukin 2.
- Low affinity form: Monomer of the alpha subunit, not involved in signal transduction.
- Intermediate affinity form: Alpha/beta subunit heterodimer.
- High affinity form: Alpha/beta/gamma subunit heterotrimer.
Both intermediate and high affinity forms are involved in receptor-mediated endocytosis and mitogenic signal transduction from interleukin 2.
The encoded protein represents the beta subunit, a type I membrane protein primarily expressed in the hematopoietic system.
Alternative promoters result in multiple transcript variants encoding the same protein.
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