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ELK Biotechnology IL-2Rβ (phospho Tyr364) rabbit pAb
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ELK Biotechnology IL-2Rβ (phospho Tyr364) rabbit pAb

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IL-2Rβ (phospho Tyr364) rabbit polyclonal antibody로, IL-2 수용체 베타 소단위의 인산화 부위를 인식합니다. WB, IF, ELISA에 사용 가능하며, 인간, 마우스, 랫트에 반응합니다. 세포막 단일 통과형 단백질 검출에 적합합니다.

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pk
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ELK Biotechnology ES5872-100UL IL-2Rβ (phospho Tyr364) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES5872-50UL IL-2Rβ (phospho Tyr364) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology IL-2Rβ (phospho Tyr364) rabbit pAb

제품명

IL-2Rβ (phospho Tyr364) rabbit pAb

제품 정보

항목 내용
Alternative Names IL2RB; Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; High affinity IL-2 receptor subunit beta; p70-75; p75; CD antigen CD122
Applications WB; IF; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
Immunofluorescence: 1/200 - 1/1000
ELISA: 1/10000
Not yet tested in other applications
Immunogen Synthesized peptide derived from human IL-2R beta around the phosphorylation site of Tyr364 (AA range: 331-380)
Host Rabbit
Storage -20°C, 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 61 kD
Gene ID (Human) 3560
Human Swiss-Prot No. P14784
Cellular Localization Cell membrane; Single-pass type I membrane protein
Species Reactivity Human; Mouse; Rat

Background

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, exists in three forms based on its binding affinity for interleukin 2.

  • Low affinity form: Monomer of the alpha subunit, not involved in signal transduction.
  • Intermediate affinity form: Alpha/beta subunit heterodimer.
  • High affinity form: Alpha/beta/gamma subunit heterotrimer.

Both intermediate and high affinity forms are involved in receptor-mediated endocytosis and mitogenic signal transduction from interleukin 2.
The encoded protein represents the beta subunit, a type I membrane protein primarily expressed in the hematopoietic system.
Alternative promoters result in multiple transcript variants encoding the same protein.

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