ELK Biotechnology Histone H3.3 (phospho Ser31) rabbit pAb
Histone H3.3 (phospho Ser31) rabbit pAb는 인간, 마우스, 랫트 시료에서 인산화된 Ser31 부위를 특이적으로 인식하는 폴리클로날 항체입니다. IHC, IF, ELISA에 적합하며 높은 특이성과 재현성을 제공합니다. 핵 및 염색체 내 단백질 검출에 유용합니다.
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Histone H3.3 (phospho Ser31) rabbit pAb
제품 개요
Histone H3.3 (phospho Ser31) rabbit pAb는 인간 Histone H3.3 단백질의 Ser31 인산화 부위를 인식하도록 제작된 폴리클로날 항체입니다. 핵 및 염색체 내 히스톤 단백질 연구에 활용됩니다.
스펙 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3.3 (phospho Ser31) rabbit pAb |
| Alternative Names | H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | IHC: 1/100 - 1/300 IF: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Histone H3.3 around phosphorylation site of Ser31 (AA range: 16–65) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 3020 / 3021 |
| Human Swiss-Prot No | P84243 |
| Cellular Localization | Nucleus; Chromosome |
| Species Reactivity | Human; Mouse; Rat |
Background
Histones are basic nuclear proteins responsible for nucleosome structure in eukaryotic chromosomal fibers. Two molecules of each core histone (H2A, H2B, H3, and H4) form an octamer, around which ~146 bp of DNA is wrapped to form nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes, aiding chromatin compaction. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The encoded protein is a replication-independent member of the histone H3 family. [RefSeq, Jul 2008]
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