
ELK Biotechnology MRP-L22 rabbit pAb
MRP-L22 rabbit pAb는 인간, 마우스, 랫트에 반응하는 폴리클로날 항체로, 미토콘드리아 리보솜 단백질 연구에 적합합니다. WB, IHC, IF, ELISA에 사용 가능하며, 고순도 IgG 형태로 안정적 저장(-20°C, 1년) 가능합니다.
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제품명
MRP-L22 rabbit pAb
제품 개요
MRP-L22 rabbit pAb는 인간 MRPL22 유래 합성 펩타이드(AA 91–140)를 면역원으로 제작된 폴리클로날 항체입니다. 미토콘드리아 리보솜 단백질 L22 연구에 활용되며, 다양한 실험 응용(WB, IHC, IF, ELISA)에 적합합니다.
주요 정보
| 항목 | 내용 |
|---|---|
| Product name | MRP-L22 rabbit pAb |
| Alternative Names | MRPL22; MRPL25; RPML25; HSPC158; 39S ribosomal protein L22, mitochondrial; L22mt; MRP-L22; 39S ribosomal protein L25, mitochondrial; L25mt; MRP-L25 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/10000 Other applications: Not yet tested |
| Immunogen | Synthesized peptide derived from human MRPL22 (AA range: 91–140) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 24 kDa |
| GeneID (Human) | 29093 |
| Human Swiss-Prot No. | Q9NWU5 |
| Cellular Localization | Mitochondrion |
| Species Reactivity | Human; Mouse; Rat |
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within the mitochondrion. Mitochondrial ribosomes consist of a small 28S subunit and a large 39S subunit, with an estimated 75% protein to rRNA ratio, in contrast to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack 5S rRNA. The proteins comprising the mitoribosome vary significantly among species, making sequence homology recognition difficult. The MRPL22 gene encodes a 39S subunit protein belonging to the L22 ribosomal protein family. A pseudogene corresponding to this gene exists on chromosome 4q, and two transcript variants encoding different isoforms have been identified.
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