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ELK Biotechnology INPP5J rabbit pAb
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ELK Biotechnology INPP5J rabbit pAb

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INPP5J 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 사용 가능. 세포질 및 막 주름에 주로 국한됨. 고순도 IgG 형태로 제공되며, -20°C에서 1년 보관 가능.

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pk
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ELK Biotechnology ES5542-100UL INPP5J rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES5542-50UL INPP5J rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology INPP5J rabbit pAb

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INPP5J rabbit pAb

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항목 내용
Alternative Names INPP5J; PIB5PA; PIPP; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; Inositol polyphosphate 5-phosphatase J
Applications IHC; IF; ELISA
Recommended Dilutions Immunohistochemistry: 1/100 - 1/300
ELISA: 1/40000
Not yet tested in other applications
Immunogen Synthesized peptide derived from INPP5J (AA range: 850–930)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Gene ID (Human) 27124
Human Swiss-Prot No. Q15735
Cellular Localization Cytoplasm. Predominantly localized to membrane ruffles.
Species Reactivity Human; Rat

Background

  • Catalytic activity:
    • 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H₂O → 1D-myo-inositol 1,3,4-trisphosphate + phosphate
    • D-myo-inositol 1,4,5-trisphosphate + H₂O → myo-inositol 1,4-bisphosphate + phosphate
  • Domain: The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein.
  • Function: Inositol 5-phosphatase converting inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also acts on phosphatidylinositol 4,5-bisphosphate and inositol 1,3,4,5-tetrakisphosphate in vitro. May modulate membrane ruffle-associated inositol and phosphatidylinositol polyphosphate-binding proteins.
  • PTM: Phosphorylated at Ser/Thr residues.
  • Similarity: Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family.
  • Subcellular location: Predominantly localized to membrane ruffles.

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