
ELK Biotechnology Dynein IC1 rabbit pAb
Dynein IC1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. 인간 DNAI1 유래 펩타이드로 면역화되었으며, 세포질 및 섬모 축사에 위치한 단백질 검출에 활용됩니다.
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Dynein IC1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Dynein IC1 rabbit pAb |
| Alternative Names | DNAI1; Dynein intermediate chain 1; axonemal; Axonemal dynein intermediate chain 1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DNAI1. AA range: 211-260 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 79 kD |
| Gene ID (Human) | 27019 |
| Human Swiss-Prot No. | Q9UI46 |
| Cellular Localization | Dynein axonemal particle; Cytoplasm, cytoskeleton, cilium axoneme |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. (RefSeq, Jul 2013)
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