ELK Biotechnology TIMAP rabbit pAb
인간 PPP1R16B 유래 펩타이드로 제작된 TIMAP rabbit polyclonal antibody. WB 및 IHC에 적합하며 세포막 및 핵에서 발현 확인. 고순도 IgG 형식으로 안정적 장기 보관 가능.
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제품명
TIMAP rabbit pAb
제품 개요
ELK Biotechnology에서 제공하는 TIMAP rabbit polyclonal antibody는 인간 PPP1R16B 유래 합성 펩타이드로 제작되었습니다. 세포막 및 핵에서 발현되는 단백질 검출에 사용되며, WB 및 IHC 분석에 적합합니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Alternative Names | PPP1R16B; ANKRD4; KIAA0823; Protein phosphatase 1 regulatory inhibitor subunit 16B; Ankyrin repeat domain-containing protein 4; CAAX box protein TIMAP; TGF-beta-inhibited membrane-associated protein; hTIMAP |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | Synthesized peptide derived from human PPP1R16B (AA range: 364–413) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 64 kD |
| GeneID (Human) | 26051 |
| Human Swiss-Prot No | Q96T49 |
| Cellular Localization | Cell membrane; Lipid-anchor; Nucleus; Cell projection. Colocalizes with RPSA/LAMR1 in the cell membrane (PubMed:16263087). Localizes to the perinuclear region (By similarity). Colocalizes with PTEN at the tip of EC projections (PubMed:25007873). |
| Species Reactivity | Human; Mouse |
Background
The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. (RefSeq, Sep 2015)
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