Thermo Fisher Scientific Gemin 4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Gemin 4. Recombinant protein control fragment (Product #RP-104285). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Gemin 4,uniProtId:P57678-1,ncbiNodeId:9606,antigenRange:338-438,antigenLength:1058,antigenImageFileName:PA5-64346_Gemin_4_P57678-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64346_Gemin_4_P57678-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641953

Product Specific Information

Immunogen sequence: SQGTSYDSYR LCDSLTSFSQ NATLYLNRTS LSKEDRQVVS ELAECVRDFL RKTSTVLKNR ALEDITASIA MAVIQQKMDR HMEVCYIFAS EKKWAFSDEW V

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 78%.

Target Information

The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies. The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.