Thermo Fisher Scientific FOXB2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FOXB2. Recombinant protein control fragment (Product #RP-104147). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FOXB2,uniProtId:Q5VYV0-1,ncbiNodeId:9606,antigenRange:276-321,antigenLength:432,antigenImageFileName:PA5-64351_FOXB2_Q5VYV0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64351_FOXB2_Q5VYV0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641714

Product Specific Information

Immunogen sequence: IGRDYKGVLQ AGGLPLASVM HHLGYPVPGQ LGNVVSSVWP HVGVMD

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Target Information

The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and maybe associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are membersof the FOX family and each contain one forkhead DNA-binding domain.Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded evelopment of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.