Thermo Fisher Scientific FOXB2 Polyclonal Antibody
Human FOXB2 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 제공. 장기 보관 시 -20°C에서 안정적으로 유지.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FOXB2. Recombinant protein control fragment (Product #RP-104147) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641714 |
Product Specific Information
Immunogen sequence:
IGRDYKGVLQ AGGLPLASVM HHLGYPVPGQ LGNVVSSVWP HVGVMD
Antigen sequence identity:
- Mouse: 96%
- Rat: 96%
Target Information
The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins involved in transcriptional regulation and may be associated with the pathogenesis of various cancers.
FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain.
Both FOXB1 and FOXB2 localize to the nucleus, functioning as transcription factors that can bind DNA via their forkhead domains.
In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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