Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI2H8), TrueMAB
CD4 단백질을 인식하는 mouse monoclonal antibody로, Western blot 및 IHC(P)에서 검증됨. Human CD4 full-length 단백질을 면역원으로 제작. Affinity chromatography로 정제된 액상 제품으로, -20°C에서 보관하며 연구용으로 사용.
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- TA800524
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H8 |
| Immunogen | Full length human recombinant protein of human CD4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV.
CD4 is primarily expressed in T helper cells but can also be found in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression is detected in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut.
CD4 contributes to T-cell activation through association with the T-cell receptor complex and Lck kinase, and may mediate neuronal damage in infectious and immune-mediated CNS diseases.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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