Thermo Fisher Scientific Phospho-BCLAF1 (Ser531) Polyclonal Antibody
BCLAF1 단백질의 Ser531 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 적합하며, 사람, 마우스, 랫트 시료에 반응. 액상 형태, 1 mg/mL 농도, PBS/glycerol buffer에 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BCLAF1 (Accession Q9NYF8), corresponding to amino acid residues around phosphorylated Ser531 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903178 |
Product Specific Information
This antibody detects endogenous levels of BCLAF1 only when phosphorylated at Ser531.
Target Information
BCLAF1 (BCL2-associated transcription factor 1) is an intracellular, death-promoting transcriptional repressor that interacts with multiple members of the BCL2 family. It contains basic leucine zipper (bZIP) and MYB DNA-binding domains. In apoptotic cells, BCLAF1 localizes to dot-like structures throughout the nucleus and redistributes near the nuclear envelope. Overexpression induces apoptosis, which can be inhibited by co-expression of BCL2 proteins. Also known as BTF, it triggers a pro-apoptotic signal and is mainly expressed in skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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