Thermo Fisher Scientific SRC Polyclonal Antibody
SRC 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 인간·마우스·랫트 반응성을 보입니다. 연구용으로 세포 성장 및 신호전달 관련 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
- Publications: References
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within C-terminal human SRC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932453 |
Target Information
SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth. It regulates growth and differentiation of eukaryotic cells and associates with the cytoplasmic region of various cell surface receptors to facilitate signal transduction. SRC also plays roles in cytoskeletal organization, cell cycle regulation, and apoptosis.
In humans, the SRC gene is located on chromosome 20. Its activity is regulated by phosphorylation at Tyr416 and Tyr527, which have opposing effects on enzyme activity. Mutations in SRC may contribute to malignant progression of colon cancer. Two transcript variants encoding the same SRC protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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