Thermo Fisher Scientific PAICS Monoclonal Antibody (OTI1B4), TrueMAB
PAICS 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, ICC/IF, Flow cytometry에 사용 가능. HEK293T 세포에서 발현된 full-length human recombinant protein을 면역원으로 사용. 동결건조 형태, PBS buffer에 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B4 |
| Immunogen | Full length human recombinant protein of human PAICS produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a bifunctional enzyme containing:
- Phosphoribosylaminoimidazole carboxylase activity (N-terminal region)
- Phosphoribosylaminoimidazole succinocarboxamide synthetase activity (C-terminal region)
It catalyzes steps 6 and 7 of purine biosynthesis.
The gene is closely linked and divergently transcribed with another locus in the same pathway, and transcription of the two genes is coordinately regulated.
The human genome contains several pseudogenes of this gene, and multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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