Thermo Fisher Scientific Liver X Receptor beta (LXRB) (Orphan Receptor) Monoclonal Antibody (LXRB/2731)
Liver X Receptor beta(LXRB)에 특이적인 단클론 항체로, 인간 시료에서 사용 가능. ELISA 및 Peptide Array에 적용 가능하며, 단백질 A/G 정제된 액상 형태로 제공. 4°C에서 보관하며 동결 금지. 연구용으로만 사용.
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Applications
- ELISA (ELISA): Assay-dependent
- Peptide Array (Array): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LXRB/2731 |
| Immunogen | Recombinant full-length human NR1H2 (LXRB) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation.
The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed.
Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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