Thermo Fisher Scientific IL-3 Monoclonal Antibody (BVD3-1F9), Biotin
Human IL-3에 특이적인 Rat monoclonal antibody (Clone BVD3-1F9), Biotin 결합형. ELISA에 최적화되어 있으며, 0.5 mg/mL 농도의 액상 정제 제품. 혈액세포 성장인자 연구용으로 적합하며, 4°C 보관.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:2,000–1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BVD3-1F9 |
| Immunogen | Yeast-expressed human IL-3 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4, with proprietary stabilizer |
| Contains | <0.1% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745598 |
Additional Formats
Target Information
Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
Most of these functions are enhanced or dependent on co-stimulation with other cytokines.
Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and the bioactivity of IL-3 is highly species-specific.
Human IL-3 has no activity on mouse cells.
IL-3 supports proliferation of a broad range of hematopoietic cell types and is involved in cell growth, differentiation, and apoptosis.
It also possesses neurotrophic activity and may be associated with neurologic disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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