Thermo Fisher Scientific WDR92 Polyclonal Antibody
WDR92 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC에 적합하며 인간과 생쥐 시료 반응. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공. 냉장 또는 냉동 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 21 amino acid peptide near the center of human WDR92 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153216 |
Product Specific Information
- Suggested positive control: human kidney tissue lysate
- PA5-21012 can be used with blocking peptide PEP-1126
Target Information
WD40 repeats are a common structural module in eukaryotic proteins. Proteins containing WD40 domains have diverse functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription.
WDR92 (also known as monad) contains two WD40 repeats and is widely expressed in human tissues, particularly in the testis. Overexpression of WDR92 or its binding partner RNA polymerase II-associated protein 3 (RPAP3) enhances apoptosis and caspase-3 activation induced by TNF-α and cycloheximide, suggesting that WDR92 and RPAP3 may act as modulators of apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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