Thermo Fisher Scientific FBXL2 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: A431, HeLa, HepG2, Raji
• Predicted reactivity: Bovine (100%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a member of the F-box protein family, characterized by an approximately 40 amino acid motif, the F-box.
The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1–cullin–F-box), which function in phosphorylation-dependent ubiquitination.
F-box proteins are divided into three classes:

• Fbws containing WD-40 domains
• Fbls containing leucine-rich repeats
• Fbxs containing either different protein–protein interaction modules or no recognizable motifs

The protein encoded by this gene belongs to the Fbls class, containing an F-box and 12 tandem leucine-rich repeats.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.