Thermo Fisher Scientific Runx3 Polyclonal Antibody
RUNX3 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P)에서 사용 가능. 인간 및 랫드 반응성. 합성 펩타이드(aa 160-210)로 면역화됨. 동결건조 형태로 제공되며 4°C 또는 -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:300 | – |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 160–210 of human RUNX3 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: Runx3.
Target Information
This gene encodes a member of the runt domain-containing family of transcription factors.
A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3', found in various enhancers and promoters, and can either activate or suppress transcription.
It also interacts with other transcription factors and functions as a tumor suppressor.
The gene is frequently deleted or transcriptionally silenced in cancer.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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