Thermo Fisher Scientific Cytokeratin 14 Recombinant Mouse Monoclonal Antibody (LL002)
Human Cytokeratin 14을 인식하는 mouse recombinant monoclonal antibody로, WB, IHC, ICC/IF, Flow, IP 등 다양한 assay에 사용 가능. HEK293F 발현, IgG2a isotype, 1 mg/mL 농도의 액상 형태로 제공되며, 4°C 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | LL002 |
| Immunogen | Human Cytokeratin 14 (C terminal) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells found in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs have been identified. Most CKs belong to one of two biochemical classes: type I (acidic polypeptides) or type II (basic polypeptides).
Keratin 14, a type I low molecular weight keratin, pairs with keratin 5 and serves as a marker distinguishing stratified epithelial cells from simple epithelial cells. It is valuable for identifying squamous cell carcinomas and is considered a prognostic marker in breast carcinomas.
Each epithelial cell expresses at least one member of the acidic and one of the basic keratin families.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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