Thermo Fisher Scientific SIM2 Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SIM2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SIM2,uniProtId:Q14190-1,ncbiNodeId:9606,antigenRange:324-468,antigenLength:667,antigenImageFileName:PA5-56105_SIM2_Q14190-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56105_SIM2_Q14190-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647308

Product Specific Information

Immunogen sequence: CIVSVNYVLT EIEYKELQLS LEQVSTAKSQ DSWRTALSTS QETRKLVKPK NTKMKTKLRT NPYPPQQYSS FQMDKLECGQ LGNWRASPPA SAAAPPELQP HSESSDLLYT PSYSLPFSYH YGHFPLDSHV FSSKKPMLPA KFGQP

Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.

Target Information

This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.