Thermo Fisher Scientific AVPR2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human AVPR2 for WB and ICC/IF applications. Recognizes amino acids 80–130 of AVPR2. Affinity-purified, >95% purity, supplied as liquid form at 1 mg/mL. Suitable for research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 80–130 of Human AVPR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719137 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. Purity is >95% (by SDS-PAGE).
Target Information
Avpr2 is a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone synthesized in the supraoptic and paraventricular nuclei of the hypothalamus. Together with neurophysin 2, it is packaged into neurosecretory vesicles and transported to the neurohypophysis, where it is stored or secreted into the bloodstream. Avpr2 acts as a growth factor by enhancing pH regulation through acid-base transport systems and has a direct antidiuretic action on the kidney. It also causes vasoconstriction, smooth muscle contraction during parturition and lactation, and is involved in cognition, tolerance, adaptation, and complex sexual and maternal behavior. Its activity is mediated by G proteins that activate adenylate cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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