Thermo Fisher Scientific CDS1 Polyclonal Antibody
인간 CDS1 단백질에 특이적인 Rabbit Polyclonal 항체. IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제. PBS 기반 완충액에 40% 글리세롤 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CDS1. Recombinant protein control fragment (Product #RP-96708). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639627 |
Product Specific Information
Immunogen sequence:
YQYFVCPVEY RSDVNSFVTE CEPSELFQLQ TYSLPPFLKA VLRQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 91%
Target Information
Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity.
This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol.
This enzyme is an integral membrane protein localized to two subcellular domains:
- The matrix side of the inner mitochondrial membrane, where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin.
- The cytoplasmic side of the endoplasmic reticulum, where it functions in phosphatidylinositol biosynthesis.
Two genes encoding this enzyme have been identified in humans, one mapping to chromosome 4q21 and a second to 20p13.
[provided by RefSeq, Jul 2008]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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