Thermo Fisher Scientific TMEM48 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 340-530 of human NDC1 (NP_0605573) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TMEM48,uniProtId:Q9BTX1-1,ncbiNodeId:9606,antigenRange:340-530,antigenLength:674,antigenImageFileName:PA5-116770_TMEM48_Q9BTX1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116770_TMEM48_Q9BTX1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.84 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901401

Product Specific Information

Positive Samples: MCF7, Jurkat, HeLa, Mouse heart, Mouse brain

Immunogen sequence: QYSPSRRQEV FSLSQPGGHP HNWTAISREC LNLLNGMTQK LILYQEAAAT NGRVSSSYPV EPKKLNSPEE TAFQTPKSSQ MPRPSVPPLV KTSLFSSKLS TPDVVSPFGT PFGSSVMNRM AGIFDVNTCY GSPQSPQLIR RGPRLWTSAS DQQMTEFSNP SPSTSISAEG KTMRQPSVIY SWIQNKREQI K

Target Information

TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.