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Thermo Fisher Scientific PRRX2 Polyclonal Antibody
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Thermo Fisher Scientific PRRX2 Polyclonal Antibody

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PRRX2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응. Western blot 및 ELISA에 적합하며, 고순도 Affinity Chromatography 정제. PBS/glycerol buffer로 안정적 보관 가능.

카탈로그번호
PA5120752
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오전 12:59
Thermo Fisher Scientific PA5120752 PRRX2 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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710,700원VAT 포함 781,770원

Thermo Fisher Scientific · Thermo Fisher Scientific PRRX2 Polyclonal Antibody

Applications

Western Blot (WB)

  • Tested Dilution: 1:500–1:1,000

ELISA

  • Tested Dilution: 1 µg/mL

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 180–253 of human PRRX2 (NP_057391.1)
Conjugate Unconjugated
Form Liquid
Concentration 1.055 mg/mL
Purification Affinity Chromatography
Storage Buffer PBS, pH 7.3, with 50% glycerol
Contains 0.05% ProClin 300
Storage Conditions −20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Wet ice
RRID AB_2914324

Product Specific Information

Positive test controls include:

  • NIH/3T3
  • Mouse brain
  • Mouse skin
  • Mouse spleen
  • Rat testis

Immunogen sequence:
QEAAIEQPVA PRPTALSPDY LSWTASSPYS TVPPYSPGSS GPATPGVNMA NSIASLRLKA KEFSLHHSQV PTVN


Target Information

The paired-class homeobox genes PRX1 and PRX2 are essential for craniofacial and limb development and are expressed in similar patterns in the cranial mesenchyme, limb buds, axial mesoderm, and branchial arches.
However, they differ in heart and brain expression:

  • PRX1 is expressed in endocardial cushions, valves, and ventral hypothalamus.
  • PRX2 is expressed in myocardial tissue and ventricular septum but not in the brain.

Mice lacking PRX1 show skeletal defects, while PRX2-deficient mice do not. Double mutants (PRX1/PRX2) exhibit novel skeletal abnormalities.
PRX gene expression is induced in vascular disease and co-localizes with Tenascin-C expression sites.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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