Thermo Fisher Scientific Cdc42EP5 Polyclonal Antibody
Human Cdc42EP5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Cdc42EP5. Recombinant protein control fragment (Product #RP-99145). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639567 |
Product Specific Information
- Immunogen sequence: KPDAEPRPGT QPPQARCRPN ADLELNDVIG L
- Highest antigen sequence identity to orthologs: Mouse – 58%, Rat – 52%
Target Information
Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with downstream effector proteins. The encoded protein is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins, containing a CRIB (Cdc42/Rac interactive-binding) domain. Borg family proteins bind to CDC42 and negatively regulate its function. The protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding and may play a role in septin organization and pseudopodia formation in fibroblasts.
[Provided by RefSeq, Jul 2013]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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