Thermo Fisher Scientific ABCG5 Monoclonal Antibody (1B5E10)
ABCG5 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, Flow, ELISA에 적합. 인간 시료 반응성. Protein G 정제, PBS 버퍼 및 sodium azide 함유. 연구용으로 sterol 수송 관련 연구에 활용 가능.
- 카탈로그번호
- MA531603
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B5E10 |
| Immunogen | Purified recombinant fragment of human ABCG5 (AA: 306–367) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787227 |
Product Specific Information
MA5-31603 has been tested in indirect ELISA.
Target Information
The ABCG5 gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. These proteins transport various molecules across cellular membranes. ABCG5 belongs to the White subfamily and functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in the liver, colon, and intestine. The gene is tandemly arrayed with ABCG8 on chromosome 2. Mutations may lead to sterol accumulation and atherosclerosis, and are associated with sitosterolemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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