Thermo Fisher Scientific ADAMTS13 Monoclonal Antibody (20A5)
인간 ADAMTS13 단백질을 인식하는 단클론 항체로, WB, ICC/IF, IA 등 다양한 분석에 사용 가능. Mouse IgG1 형식의 비접합 항체로, 100 µg/mL 농도. Protein G로 정제되었으며 PBS/BSA buffer에 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 20A5 |
| Immunogen | The monoclonal antibody 20A5 recognizes the central to C-terminal TSP-1 repeats 2 to 5 of ADAMTS-13 (amino acid 686–894). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3091117 |
Product Specific Information
The monoclonal antibody 20A5 recognizes human ADAMTS-13, a disintegrin and metalloprotease with thrombospondin type 1 domain 13.
Target Information
ADAMTS13 belongs to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members share several distinct modules, including a propeptide region, metalloproteinase domain, disintegrin-like domain, and thrombospondin type 1 (TS) motif. They differ in the number of C-terminal TS motifs and may have unique C-terminal domains.
ADAMTS13 functions as the von Willebrand Factor (vWF)-cleaving protease, responsible for cleavage at Tyr842-Met843 of vWF. Deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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