Thermo Fisher Scientific GARP Polyclonal Antibody
Thermo Fisher Scientific의 GARP Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB 및 IHC에 사용됩니다. Rabbit Ig 폴리클로날 항체로, 합성 펩타이드 항원 기반입니다. 동결건조 형태로 제공되며 장기보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of human GARP conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity of this antibody: GARP
Target Information
Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. GARPs are characterized by six repeated motifs of VVEKKN/EE, which help form an alpha-helix structure.
The function of GARP is not fully characterized, but studies suggest that it helps limit cGMP turnover by inhibiting phosphodiesterase activity.
Two splice variants have been identified: GARP1 (full-length) and GARP2 (truncated).
GARP also interacts with the cytoplasmic domain of the beta-subunit of the cyclic GMP-gated channel in the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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