Thermo Fisher Scientific HPD Polyclonal Antibody
HPD 단백질을 타겟으로 한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunohistochemistry(Paraffin)에 적합하며, Human, Mouse, Rat 시료에 반응. 항원 친화 크로마토그래피로 정제된 1 mg/mL 액상 항체로, 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human HPD (aa 1–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913319 |
Product Specific Information
- Positive Control: Rat liver tissue lysate, human kidney tissue lysate, rat kidney tissue, human liver tissue, mouse liver tissue
- Subcellular Location: Cytosol, endoplasmic reticulum membrane, extracellular exosome, golgi membrane
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. A serine protease called Omi/HtrA2, released from mitochondria upon apoptotic stimulation, binds to IAP. Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N-terminus. Deregulated cytoplasmic expression of Omi induces apoptosis, suggesting its role in the mitochondrial apoptotic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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