Thermo Fisher Scientific NRF1 Recombinant Rabbit Monoclonal Antibody (ARC0768)
NRF1 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체로, WB, IHC, ELISA, IP, ChIP, CUT&RUN 등 다양한 응용에 적합. 고순도 친화 크로마토그래피 정제, HEK293 발현 시스템 기반, 안정적 액상 형태로 연구용에 최적화됨.
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Thermo Fisher Scientific NRF1 Recombinant Rabbit Monoclonal Antibody (ARC0768)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5 µg–4 µg antibody for 200 µg–400 µg extracts |
| ChIP assay (ChIP) | 5 µg antibody for 10 µg–15 µg of Chromatin |
| CUT&RUN (C&R) | 10⁵ cells / 1 µg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0768 |
| Immunogen | Synthetic peptide corresponding to amino acids 300–400 of human NRF1 (Q16656) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.61 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849267 |
Product Specific Information
Immunogen sequence:
LVPSQTVVQT FSNPDGTVSL IQVGTGATVA TLADASELPT TVTVAQVNYS AVADGEVEQN WATLQGGEMT IQTTQASEAT QAVASLAEAA VAASQEMQQG A
Target Information
NRF1 encodes a transcription factor that homodimerizes and activates expression of key metabolic genes regulating cellular growth, respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. It is also associated with neurite outgrowth regulation. Alternate splice variants encoding the same protein have been characterized, and additional isoforms have been described but not fully characterized. Note that confusion may occur due to the shared symbol “NRF1” with nuclear factor (erythroid-derived 2)-like 1 (official symbol: NFE2L1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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