Thermo Fisher Scientific NRF1 Recombinant Rabbit Monoclonal Antibody (ARC0768)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Immunoprecipitation (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of

-

ChIP assay (ChIP)

5 µg antibody for 10 µg-15 µg of Chromatin

-

CUT&RUN (C&R)

105 cells /1 µg

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0768

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 300-400 of human NRF1 (Q16656) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NRF1,uniProtId:Q16656-1,ncbiNodeId:9606,antigenRange:300-400,antigenLength:503,antigenImageFileName:MA5-35366_NRF1_Q16656-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35366_NRF1_Q16656-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.61 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849267

Product Specific Information

Immunogen sequence: LVPSQTVVQT FSNPDGTVSL IQVGTGATVA TLADASELPT TVTVAQVNYS AVADGEVEQN WATLQGGEMT IQTTQASEAT QAVASLAEAA VAASQEMQQG A

Target Information

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for nuclear factor (erythroid-derived 2)-like 1 which has an official symbol of NFE2L1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.