Thermo Fisher Scientific LONP1 Polyclonal Antibody
LONP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LONP1 (Accession P36776), corresponding to amino acid residues L825–Q875 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815550 |
Product Specific Information
Antibody detects endogenous levels of total LONP1.
Target Information
The LONP1 gene encodes a mitochondrial matrix protein belonging to the Lon family of ATP-dependent proteases. This protein mediates selective degradation of misfolded, unassembled, or oxidatively damaged polypeptides in the mitochondrial matrix. It may also function as a chaperone in the assembly of inner membrane protein complexes and participate in regulating mitochondrial gene expression and maintaining mitochondrial genome integrity. Decreased expression has been observed in a patient with hereditary spastic paraplegia. Alternatively spliced transcript variants have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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