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Thermo Fisher Scientific BRD7 Polyclonal Antibody
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BRD7 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합합니다. 인간, 생쥐, 랫트 반응성을 가지며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5100009
- 판매단위
- pk
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마지막 업데이트 2025. 08. 01. 오후 06:59
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific PA5100009 BRD7 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
747,800원VAT 포함 822,580원
Thermo Fisher Scientific · Thermo Fisher Scientific BRD7 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BRD7 (Accession Q9NPI1), corresponding to amino acid residues I185–E235 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815539 |
Product Specific Information
Antibody detects endogenous levels of total BRD7.
Target Information
BRD7 acts both as coactivator and as corepressor. It activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating GSK3B activity. It is required for TP53-mediated cell-cycle arrest in response to oncogene activation and promotes acetylation of TP53 at Lys-382, enabling efficient recruitment of TP53 to target promoters and inhibition of cell cycle progression from G1 to S phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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