Thermo Fisher Scientific CTLA-4 Polyclonal Antibody
Rabbit polyclonal antibody against human CTLA-4 for WB and ELISA applications. High specificity and affinity via antigen affinity chromatography. Suitable for research use only, provided in liquid form without preservative. Stable at 4°C short term and...
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:25,000–1:50,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CTLA-4/CD152 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866865 |
Product Specific Information
This product can be used in direct ELISA.
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed mainly on CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity. Unlike CD28, which enhances T cell function, CTLA4 inhibits T cell activation and prevents its function. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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